| 67501. | ▲ | Gateway 2000's hilariously bad ads in the 90s (Part II) (buttondown.com) |
| 119 points by rfarley04 4 days ago | 100 comments |
|
| 67502. | ▲ | Lessons learned from the fate of AstraZeneca's drug pipeline (pubmed.ncbi.nlm.nih.gov) |
| 4 points by brandonb 11 hours ago | 1 comments |
|
| 67503. | ▲ | Assembly Hall of Shame (github.com) |
| 432 points by piotrgrabowski 5 days ago | 112 comments |
|
| 67504. | ▲ | Tuxedo No. 2 – Cocktail recipes (tuxedono2.com) |
| 129 points by smartmic 3 days ago | 39 comments |
|
| 67505. | ▲ | Melatonin impairs morning cognition in healthy young adults (2023) (academic.oup.com) |
| 185 points by bohaska 3 days ago | 206 comments |
|
| 67506. | ▲ | Appetite-suppressing hormone may protect liver from inflammation (medicalxpress.com) |
| 11 points by brandonb 16 hours ago |
|
| 67507. | ▲ | Changes at Google DeepMind: Demis Hassabis from CEO to Chair, Jeff Dean departs (blog.google) |
| 864 points by colesantiago 7 days ago | 932 comments |
|
| 67508. | ▲ | Auto mode is now the default in Claude Code (claude.com) |
| 289 points by sbehere 2 days ago | 310 comments |
|
| 67509. | ▲ | From your doorbell to your home network (adepts.of0x.cc) |
| 92 points by mmoogle 7 days ago | 13 comments |
|
| 67510. | ▲ | When Agentic Glue Melts: Exploiting Cloudflare Code Mode and Workers (research.checkpoint.com) |
| 23 points by shahartal 2 days ago | 1 comments |
|
| 67511. | ▲ | DeepSeek V4 Flash 0731: 82.7% on Terminal-Bench 2.1 with a public harness (antigma.ai) |
| 37 points by ubermon 3 days ago | 6 comments |
|
| 67512. | ▲ | Show HN: Higher-dimensional lattices unfolded into the 2D plane (number-garden.com) |
| 18 points by unitX 6 days ago | 1 comments |
|
| 67513. | ▲ | Show HN: I made alchemical-cosmological PCB badges (github.com) |
| 23 points by kaipereira 7 days ago | 3 comments |
|
| 67514. | ▲ | Humanity renamed genes because of Excel (davidemornatta.it) |
| 18 points by kegenaar 2 days ago | 2 comments |
|
| 67515. | ▲ | Claude Code pricing: same tokens, same model, up to 40x the price (quesma.com) |
| 30 points by jakozaur a day ago | 10 comments |
|
| 67516. | ▲ | I'm not anti-AI, but I have QUALLMS (cholling.com) |
| 13 points by CagedCoder 2 days ago | 2 comments |
|
| 67517. | ▲ | Show HN: textlog – A quiet, text-only microblogging platform, open-source, no JS (textlog.cc) |
| 205 points by stagas 5 days ago | 83 comments |
|
| 67518. | ▲ | Midlife Vascular Risk Burden and Dementia-Free Survival Years (neurology.org) |
| 83 points by bookofjoe 2 days ago | 82 comments |
|
| 67519. | ▲ | TinySol, a tiny solitaire game for DOS (classicbits.net) |
| 64 points by skibz 4 days ago | 19 comments |
|
| 67520. | ▲ | The tragedy of the commons, AI edition (economist.com) |
| 145 points by simonpure 3 days ago | 117 comments |
|
| 67521. | ▲ | Silicon Valley misreads science fiction and undermines democracy (techcrunch.com) |
| 295 points by evo_9 3 days ago | 271 comments |
|
| 67522. | ▲ | I Benchmarked Local LLMs on the Laptop I Have (mamonas.dev) |
| 20 points by konmam 2 days ago | 7 comments |
|
| 67523. | ▲ | Coinbase stopped using trading volume as a key metric after 38%/48% decrease (hachyderm.io) |
| 5 points by u1hcw9nx 12 hours ago | 1 comments |
|
| 67524. | ▲ | Making difficulty curves in games (davetech.co.uk) |
| 171 points by hakkikonu 7 days ago | 89 comments |
|
| 67525. | ▲ | Felix and I (jacobfilipp.com) |
| 26 points by surprisetalk 2 days ago |
|
| 67526. | ▲ | SEC exempts certain data center bonds from key securitization rules (reuters.com) |
| 8 points by vinyl7 12 hours ago |
|
| 67527. | ▲ | Muse Glimmer: Meta's open model built for always-on local agents. 30B parameters (developer.meta.com) |
| 12 points by helsinkiandrew 2 days ago | 2 comments |
|
| 67528. | ▲ | Danish high schoolers will have to verbally defend written assignments (mezha.net) |
| 654 points by theanonymousone 4 days ago | 283 comments |
|
| 67529. | ▲ | Triton: DirectX 11 Driver for QEMU (blog.getutm.app) |
| 214 points by electricant 4 days ago | 49 comments |
|
| 67530. | ▲ | Hardware backdoors in some x86 CPUs (github.com) |
| 379 points by epestr 4 days ago | 107 comments |
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