It's not that there's a blocker. It's that it takes roughly 3x the manufacturing capacity to produce an HBM package at the same storage capacity as DRAM. We are sacrificing total bytes for bandwidth.

I don't fully understand the source of the "total bytes" constraint, but a major factor may be because HBM4 / HBM4E can only make use of the footprint directly above the processor/logic die (or in direct vicinity of its interconnect), while traditional DRAM can be placed further away where there's lots of real estate on the motherboard.

I gather a practical max ceiling today is a stack of 16 chips in height yielding 64GB?

These chips have a massive bus size of 2048 bits, instead of the 64 or 128 bits (dual channel) used by DDR5. That's what gives them their order-of-magnitude bandwidth speedup. But even though they technically pack in more capacity per square millimeter of motherboard, I gather they take up more space than older technologies once you account for the vias and interconnects to route all those signals.

How so? FEOL is pretty much the same, BEOL is almost the same save TSVs, the packaging tech is different and more advanced, but not exactly 1:1 comparable. Do TSVs really occupy 3x the area of DDR IO's?