| ▲ | Google DeepMind Releases AlphaGenome Atlas(blog.google) |
| 207 points by utiiiD 2 hours ago | 43 comments |
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| ▲ | jFmDRz73 an hour ago | parent | next [-] |
| This Google blog post is a distilled version of a Deep Mind blog post: https://deepmind.google/blog/alphagenome-atlas-a-predictive-... They are only announcing a cache. The origin for the cache is not discussed. In particular, the question of whether to trust the predictions is not addressed. For that, I think the citation is from January: https://www.nature.com/articles/s41586-025-10014-0 |
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| ▲ | leopoldj an hour ago | parent | prev | next [-] |
| Videos. [2] is for the scientists to start using AlphaGenome Atlas from AntiGravity. 1. https://www.youtube.com/watch?v=U0aToL5C-bQ 2. https://www.youtube.com/watch?v=b2qw3rDNX0Q |
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| ▲ | RobotToaster 32 minutes ago | parent | prev | next [-] |
| Can this be used with a 23andMe genome to find pathogenic mutations? |
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| ▲ | realcul 12 minutes ago | parent | prev | next [-] |
| So I will know which DNAs to change to become a wolverine! yay! |
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| ▲ | bonsai_spool 41 minutes ago | parent | prev | next [-] |
| This may not be anything new but it makes using several Google/DeepMind resources a lot less painful. I'm comfortable programming but others who also do mol bio may be less so or may not recognize when Claude is going off the rails. |
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| ▲ | asxndu 2 hours ago | parent | prev | next [-] |
| I really love Deep Mind, its genuinely focused on using AI to make the world a better place. |
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| ▲ | sssilver an hour ago | parent | next [-] | | Be careful when loving shareholder-driven endeavors; they're a single executive decision away from breaking your heart. | | |
| ▲ | mdp2021 an hour ago | parent | next [-] | | It's "shareholder-linked" (probably not "driven"), but yes, upvoted. Nonetheless, even when with grave faults in the path, Google has managed to give us marvellous, paramount free resources (Google Street, Google Museum...), and would have given more (Google Books - if the negotiation had succeeded). I am grateful. | | |
| ▲ | boelboel 27 minutes ago | parent [-] | | Google Streetview/maps isn't even the best mapping/'streetview' tool at this point. Filled with ads and bugs, some major bugs have been there for 10+ years. | | |
| ▲ | minimeow 21 minutes ago | parent [-] | | Now I'm curious. What is the better mapping and streetview tool at this point? |
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| ▲ | panarky an hour ago | parent | prev [-] | | Be careful when loving government/philanthropy/ngo-driven endeavors; they're a single executive decision away from breaking your heart. | | |
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| ▲ | dgellow an hour ago | parent | prev [-] | | No AI company is doing that. There is some benefits but that’s not what any AI for profit will ever focus upon | | |
| ▲ | heaney-555 an hour ago | parent [-] | | DeepMind objectively is doing that. The world is not so black and white as "evil profit-hungry corporations will never do anything good". | | |
| ▲ | surgical_fire 10 minutes ago | parent | next [-] | | If Google does anything good for the world it is entirely accidental, and I am certain they will correct this mistake later. | | |
| ▲ | godwinson__4-8 2 minutes ago | parent [-] | | Market reward is the best proxy for good we have. What's your alternative? Executive fiat? Mob rule? Deepmind is objectively good. These endeavors would always cost money. Better private capital than state, no one has to give Google anything. The state is not so generous. |
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| ▲ | dgellow an hour ago | parent | prev [-] | | I preemptively acknowledged that in my comment… |
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| ▲ | gavinray 39 minutes ago | parent | prev | next [-] |
| Anyone know if you can use an indel VCF file with this? |
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| ▲ | MahiroHirakawa an hour ago | parent | prev | next [-] |
| Cool.
But is this actually advanced biology, or just making predictions about biology more accurate?
Those aren't the same thing. |
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| ▲ | searine 25 minutes ago | parent | prev | next [-] |
| I saw a really interesting talk by Katie Pollard at ISMB this year about the limitations of variant prediction. The gist was, can existing variation provide enough context to infer impact of variation? The answer seemed to be no. Kind of like how frontier LLMs need to ingest larger and large amounts of text to advance. We are going to need to leverage comparative data from other species, and likely tremendous amounts of laboratory mutagenesis experiments to actually make headway on variant prediction. Nature, as it stands, just doesn't have enough human variation. |
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| ▲ | dotinvictim an hour ago | parent | prev | next [-] |
| unleash gemini 4 stop saving dario |
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| ▲ | mertcikla 2 hours ago | parent | prev | next [-] |
| not my field so I can't judge how useful it is but assuming this data can be used for drug discovery and their ToS limiting to non-commercial use only. Does DeepMind plan on selling this data to pharmaceutical companies? |
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| ▲ | dekhn 2 hours ago | parent | next [-] | | Individual SNP predictions are not useful for drug discovery. Pharma might license this, but mainly out of fear of missing out. | |
| ▲ | abirch 2 hours ago | parent | prev | next [-] | | Probably. I know Google has partnerships with Pharma:
https://www.merck.com/news/merck-and-google-cloud-partner-to... | |
| ▲ | falcor84 2 hours ago | parent | prev | next [-] | | My understanding is that they already are, via Isomorphic Labs | |
| ▲ | bpodgursky 2 hours ago | parent | prev | next [-] | | It's a bigger deal for diagnostics than for drug development. | |
| ▲ | PunchTornado 2 hours ago | parent | prev [-] | | Hopefully. Tired, as a shareholder, to see the giveaways that deepmind is doing. | | |
| ▲ | jakkos an hour ago | parent | next [-] | | Yeah, screw enabling life changing medical research, won't someone please think of the investors' financial returns?? | |
| ▲ | boston_clone an hour ago | parent | prev [-] | | Astroturfing, eh? This is verbatim the same comment as another user in this thread. Strange... | | |
| ▲ | incognito124 an hour ago | parent [-] | | PunchTornado was first, fr2029 was second | | |
| ▲ | fr2029 an hour ago | parent [-] | | i made no such comment. reported for harassment. | | |
| ▲ | idiotsecant 42 minutes ago | parent | next [-] | | so you just happen to be posting in a thread where some random user said you made a comment but you made no comments whatsoever | |
| ▲ | Larrikin 29 minutes ago | parent | prev [-] | | You deleted the verbatim comment after it was pointed out. One was in thread and one was a stand alone comment. I was curious which was the throwaway so clicked into both profiles |
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| ▲ | orliesaurus an hour ago | parent | prev | next [-] |
| the Google DeepMind PR team can't catch a break, shame it makes no sense to me - if someone's in the field maybe they could explain to the rest of us if this is a big deal, just a PR move, or nah? |
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| ▲ | dgellow an hour ago | parent | next [-] | | Just wait a few months, if it is a big deal that will likely be obvious by then | | | |
| ▲ | dyauspitr an hour ago | parent | prev [-] | | What are you even talking about? What do you mean catch a break? They’ve made massive contributions over the last decade. | | |
| ▲ | DroneBetter an hour ago | parent [-] | | I think orliesaurus meant the PR team is unable to rest because the rest of Deepmind is so prolific and keep coming out with new things for them to announce | | |
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| ▲ | WarmWash an hour ago | parent | prev | next [-] |
| Google doing work to uncover the pandoras box of genetics? How long before they shove this under the rug... |
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| ▲ | parasxos 2 hours ago | parent | prev [-] |
| An atlas of the human genome from the company whose other atlas still routes me into a lake. |
