| ▲ | davisr 5 hours ago |
| So all I gotta do is eat some poop and it will save me from becoming a handsome, funny, unique genius? |
|
| ▲ | LoganDark 5 hours ago | parent | next [-] |
| Well no, what they're saying is it seems to be capable of reducing autism-related struggles and misbehavior, not that it can somehow remove autism. Truly removing autism in any meaningful way is probably impossible since the brain was trained with it since birth. |
| |
| ▲ | roywiggins 5 hours ago | parent [-] | | No, that appears to be the implication of this study, which frankly seems like such a large effect that I'm pretty skeptical! I'd say "where's the control group" except the claimed effect is so large that you kind of don't need one, if it's real: > Prior to the study, 83% of participants had "severe" autism. Two years later, only 17% were rated as severe, 39% as mild or moderate, and incredibly, 44% were below the cut-off for mild ASD. Emphasis mine. If you are below the cutoff for mild ASD you wouldn't be diagnosed at all. | | |
| ▲ | ebiederm 3 hours ago | parent | next [-] | | My reasing of the study is children with significant gut issues and diagnosed with autism see a significant reduction in symptoms when the gut issues are treated. Which leads me to wonder if for some of these children is the root cause just gut issues. If all they have figured out how to so is treat significant gut issues that sounds very promising. | |
| ▲ | saalweachter 5 hours ago | parent | prev | next [-] | | That was the study without a control; for the placebo controlled study, they don't give the numbers, just say "statistically significant improvements" on several metrics. (Without a control group, you have questions about how people of that age generally progress, and what other treatment/therapies they receive over those 2 years. The phase 1 trial was with children whose parents presumably sought ever possible way to help them, while the placebo controlled phase 2 was adults who may have plateaued.) | |
| ▲ | LoganDark 5 hours ago | parent | prev [-] | | > If you are below the cutoff for mild ASD you wouldn't be diagnosed at all. That makes sense, since ASD is a disorder classification and is mainly relevant for treatment and benefits. Plenty of autistic people are not diagnosed with ASD. The article certainly could do more to differentiate between the autistic spectrum itself and the diagnosis of ASD, but as long as you know not to conflate the two, it seems perfectly clear to me. | | |
|
|
|
| ▲ | quux 5 hours ago | parent | prev | next [-] |
| You don't eat it, don't be silly.... you stick the poop up your butt |
| |
| ▲ | saalweachter 5 hours ago | parent | next [-] | | I believe the best procedure is actually sticking it in your nose. (They run a tube through your nose, down your throat, through the stomach to the top of the intestines, and introduce the bacterial slurry there.) | | |
| ▲ | giarc 4 hours ago | parent | next [-] | | That's a fairly invasive way of doing it. It can be given through pills now.
https://www.lhscri.ca/news/innovative-poop-pills-show-promis... | |
| ▲ | throw310822 5 hours ago | parent | prev | next [-] | | Makes you wonder how hard would it be to just put it in a swallowable capsule that dissolves only in the upper intestine. Also, "fecal transplant" is marketable only to weirdos. "Probiotic infusion" would work better. For those who want to gain some artistic talent, there's this (but is expensive): https://en.wikipedia.org/wiki/Artist's_Shit | | |
| ▲ | rincebrain 4 hours ago | parent [-] | | From my understanding, the problem is volume. You want to land a substantial amount of, ahem, shit in there, since don't just want it to colonize one portion of the gut, and it's got quite a lot of competition. So you would be talking a truly astonishing number of pills, I think, to compare to the volume you can manage with a tube. WP suggests that it's about 100g (or 100000mg) of actual feces then mixed in a larger volume of saline or milk, and you'd probably need to have additional volume for assumed losses and whatever coating you think would work. That is a _huge_ amount to put in pills. | | |
| ▲ | throw310822 4 hours ago | parent [-] | | Good point, but shit seems to be made of a lot of stuff- ~75% water, undigested food and fiber, fats, inorganic matter... Bacteria seem to be about ~30% of the dry weight. So of those 100 grams, you'd get maybe 7/8 grams of bacteria? If so, these could possibly be delivered by a number of small capsules taken in the course of several days. |
|
| |
| ▲ | someguyiguess 5 hours ago | parent | prev [-] | | Pretty sure there’s a shorter path to the top of the intestines than through the nose but I’m no Biologist. | | |
| ▲ | tyre 5 hours ago | parent | next [-] | | If you’re implying it is through the rectum, you’ve definitely got some bio to brush up on. The small intestine alone is >20ft long. | |
| ▲ | dacops 4 hours ago | parent | prev [-] | | There really isn't. From the mouth is basically the same distance and it contains teeth and a tongue. Through the rectum is much much much farther through meters of intestine. Through the skin creates a surgical hole that's going to be difficult to keep sterile. The shortest safe path is via the nostril. |
|
| |
| ▲ | kotaKat 4 hours ago | parent | prev [-] | | ... Back and forth, forever? | | |
|
|
| ▲ | n64controller 5 hours ago | parent | prev [-] |
| [flagged] |
| |
