Imagine something like writing a server with an /metrics HTTP endpoint that Prometheus can then scrape -- but you bind it on separate port only inside a tailnet, with an ephemeral tailnet key and name it "metrics-service-blahblah".
Now you can simply write a script that uses the tailscale API to find all "metrics-service-*" nodes in your tailnet, and then adds their IP/DNS to your prometheus scraping list. Run it every 60 seconds. Done, now you can just deploy your app anywhere on any cloud and it will get scraped and that route will never be exposed to the outer internet.
This will basically just let you attach bespoke applications and not just "computers" to your network. I suspect I will get a lot of use from it.