Tailscale and Wireguard are great. I'm an OpenZiti maintainer and I've written/spoken about application embedded zero trust for many, many years. Still it seems most devs don't think it's important for whatever reason... It'll make me happy if Tailscale is successful here and can spread the word out to get more devs interested in embedding the secure connectivity directly into the apps instead of relying on the classic underlay network and bolting on security. If that sort of thing interests you, you could check out OpenZiti. It's not Wireguard-based for better or for worse you can decide (if you do end up checking it out)