We have dozens of pain killers which are not opioid based, what do you mean? From the top of my head NSAIDs can be used, and Metamizole for example is as effective as morphium.

you got nsaids, metamizole, acetoaminophen, duolexitine. And you got a couple of more that work for neuropathic pain. The biggest problem with nsaids is that they cause bleeding and kidney failure, ulcers hence can cause stomach cancer.

Here is a site you can use too see how most pharmaco therapy is lacking.

https://pain-calculator.com/calculators/osteoarthritis-pain/

Metamizol is banned in the US, so they've robbed themselves of that