Everyone's "poo-pooing" the article because the title doesn't mention mice, but, FWIW, stories of gut biota affecting humans behavior have been documented for a while.

Memory gain is noteworthy, which is the article's "wow" factor, but everyone's just knee-jerk smirking so ... here's a few random articles to gross you out about the wild world of trading microbiota and, for better or worse, changing your personality:

  * "My butt made me crave candy."[1]
  * "Gee, I'm not bipolar anymore thanks to my husband's butt juice infusion."[2]

Crazy, right?

   [1] https://www.psychologytoday.com/us/blog/the-behavioral-microbiome/202404/hacking-an-individuals-personality-through-their-gut-contents

   [2] https://www.abc.net.au/news/2025-07-28/faecal-microbiota-transplant-credited-with-curing-bipolar/105541522

▲ zinkem an hour ago | parent | next [-]

I believe this research is totally true-- I had a lot of memories come back after

1. I stopped drinking heavily and using other drugs, i.e. marijuana

2. managed my diet to avoid heartburn without medication

3. schedule my meals so it was easier to sleep at night (always eat something for breakfast when I wake up)

I did not need any "poo infusion" or anything.

I had a gal bladder removal that didn't fix the problems the doctors thought it would and got a lot smarter about the kinds and variety of food I eat.

I believe alcohol in particular was really screwing up my gut biome and entire digestive system.

	▲	y-curious 38 minutes ago \| parent \| next [-]
		What did you do for heartburn? Just looking for ideas. I noticed reducing gluten helped me personally a lot
	▲	XorNot 8 minutes ago \| parent \| prev [-]
		Your hypothesis here though is full of complicating factors. For example >I stopped drinking heavily and using other drugs, i.e. marijuana Like the primary change you made was to cut out using a whole bunch of drugs with known, significant neurological effects.

▲ hbcondo714 3 hours ago | parent | prev | next [-]

I would recommend the site https://gutbrainaxistherapeutics.com for learning more about Microbiota Transplant Therapy (MTT) and its opportunities, especially for Autism and Pitt-Hopkins Syndrome.

	▲	y-curious 34 minutes ago \| parent [-]
		I’ll dig in more but my first question when I see this: who are the donors exactly? Like who decides what the ideal gut microbiome is and that John Doe is the guy to provide his fecal matter to the masses?

▲ jimkleiber 2 hours ago | parent | prev | next [-]

There was a South Park episode about this years ago where everyone was trying to get it from Tom Brady.

▲ 1shooner 3 hours ago | parent | prev [-]

This seems to be a recent anti-science meme to dismiss studies that use mouse models. I'm sure there is an interesting line of discussion about the strengths and limits of those models, but that's probably a complex, nuanced thread to pull, not something you blow off with a hand-waving internet comment.

	▲	inanutshellus 2 hours ago \| parent \| next [-]
		To some degree the other posts are just pointing out the misleading "assumed protagonist" of the title (which doesn't mention mice) but I was surprised to see that the majority of posts boiled down to "eek! mice!"
	▲	znpy an hour ago \| parent \| prev [-]
		I bet it started with people trying to 1-up other commenters via the usual “achtually…” and then proceeding with the “in mice” notice.