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giuliomagnifico 5 hours ago

After discontinuation of Ozempic, people start to gain the weight again (and buy again more food), that’s why the spending changes again.

SkyPuncher 41 minutes ago | parent | next [-]

Processed foods are much cheaper per calorie than "healthy" options.

GLP-1 helped me kick my cravings for junk food, but that just meant I was eating more of the "expensive" stuff. Instead of $0.50 worth of Doritos as a snack, I'm eating $1.50 worth of Greek yogurt and $1.50 worth of fruit.

FatherOfCurses 2 hours ago | parent | prev | next [-]

People must be getting prescribed this medication in a vacuum without any corresponding nutritional guidance. I can't see any way of going back to my previous eating habits, mainly because I've really had my eyes opened to how mindless some of my eating was before.

jacobthesnakob 3 hours ago | parent | prev [-]

Which is no surprise to anybody with common sense, the data for discontinuing GLP-1s show exactly the intuitive outcome. Zero diet change, zero habit change for the vast majority of users. Weight loss is accomplished via biochemical tricks to eat less volume of calorie dense junk food, rather than diet substitution. When the artificial appetite suppression ends, volume of the same food increases again leading to weight yo-yo. Plus why start to exercise when you’ve got a magic weight loss drug?

Don’t get me wrong, there are some people using these drugs to get out of a pit of inertia with weight and sedentary lifestyles. But it’s small. GLP-1 drugs will have most users hooked for life because they don’t have the discipline and motivation to maintain the weight loss without it. Cha-Ching!

rootusrootus an hour ago | parent [-]

> they don’t have the discipline and motivation to maintain the weight loss

That argument has been tried for years and yet it fails nearly 100% of the time. Should we be trying something different than claiming it's a moral issue? Or is that too scientific?

jacobthesnakob 4 minutes ago | parent [-]

Why do we need to try anything? This comes down to individualism versus collectivism.

Besides, the logical consequence of the portion of my comment you highlighted is that the majority of GLP-1 patients will need to be on these drugs forever to maintain these benefits long-term. We have precisely one trial of 5+ years of patients taking liraglutide, and ~2 years for semaglutide. Some side effects and long-term consequences could be entirely unknown.