Low Earth orbit is 90 to 120 minutes, depending on altitude. Even if the satellite is currently close to you, it will soon be on the other side of the world.

Assuming that orbital data centers make sense, it will be an interesting challenge to figure out how to best mitigate that. Short tasks that require little data will be easy, but everything else needs rethinking. Can you tolerate variable latency? Should you duplicate the data across many satellites? Or should the data constantly migrate from satellite to satellite?