...?

Your rebuttal is that GLP was a highly desirable target for a long time before we stumbled upon a way to hit it... and this is evidence that the "stumbling upon a way to hit it" was not a super critical and super fortunate event...?

> How much did gila monsters buy? Maybe a year or two?

Why'd you put "a year or two?" here and not "a decade or two?" or "a century or two?" Do you have reason to believe it was a year or two away, sans Gila monster? If so, can you provide your reasoning? Per your own point, GLP was a desirable target for a long time without successful hits. We have plenty of targets that are desirable for decades without figuring out a way to actually drug them.

Do you know the full story of glp-1 from a pharmacokinetic point of view? It seems not, since I explained clearly why I assigned a short time in my above comment.