I typically distinguish between complexity and complication when discussing biology. I don’t consider most molecular biology/biology to be complicated, rather it is “just” a hugely diverse set of largely orthogonal subsystems. Protein folding prediction kind of proves my point. The techniques of structure templating have been around since before current ML era, but it took GPUs to scale that simple technique out to the level that we could get useful structure prediction. It is fair to assume our understanding of molecular machinery can scale similarly, but we are limited in our capacity to manipulate and test these diverse things.