Remix.run Logo
▲ nly 3 days ago

I started wegovy 3 weeks ago (1.5mg oral dose) and so far have felt absolutely nothing, good or bad.

I'm assuming this is normal and something will happen when I up the dose.

▲seanmcdirmid 3 days ago | parent [-]

Ya, you are still ramping and the smaller doses are to see if there will be problems before you hit 30mg. You should notice something when you hit 10mg though.

▲gruturo 2 days ago | parent [-]

30mg is an extremely high dosage, far beyond the maximum Semaglutide (Wegovy) trials (which initially topped out at 2.4 and years later validated a new max of 7.2) and likely to land you in a hospital.

Even 10mg is very, very high, beyond the trials maximums (though preliminary small escalation trials tested that, even reaching 16mg, I guess the participants really didn’t enjoy that) and would have serious side effects if not result in a hospital visit as well.

Please be a lot more careful dispensing advice on a public forum on matters where people could get hurt.

▲iand 2 days ago | parent | next [-]

Oral Wegovy is dispensed in higher doses than injection presumably because uptake via the gut is lower.

▲JKCalhoun 2 days ago | parent [-]

Yeah, came here to say you can't compare dosages across drugs—they are in some cases an order of magnitude different.

▲seanmcdirmid 2 days ago | parent | prev [-]

I misremembered the dosage, it’s 25 mg, not 30 mg. It’s pretty standard for oral, since absorption is different from injection.