There were no PowerPC Macs in the '80s. Running Mac software on non-Apple 68k machines was a thing, though[1].

Apple itself also had a project, started in the late '80s, to port the Mac OS to x86[2].

Incidentally, PowerPC Mac OSes, especially later pre-OS X OSes like Mac OS 9.x, run quite well today on vanilla QEMU, no hacking required.

[1] https://www.atarimagazines.com/startv3n6/mac_pc_on_st.html

[2] https://en.wikipedia.org/wiki/Star_Trek_project