I think this is a geopolitical question beyond any cabinet or chair. In general, I think it would surprise people, but a Democratic cabinet would have to do many of the same geopolitical choices as Trump has done.

If you read Chokepoints by Fishman, it's for example clear that US had to do something with Iran soon, because all of the economical sanctional options were squeezed to the max, there was no offramp for that country.

Is it? Obama era actions against Iran were pulled back by the following administration and unfortunately the world will never know if Harris could have been goaded into bombing Iran the same way the current President was. Hillary Clinton, while working for the state department has stories about being told that jets were hot on the runway and the US needed to jump in as well.