Remix.run Logo
▲ JumpCrisscross 4 hours ago

> Why would the body, a master of efficiency, produce IgE just for fun?

I was being punchy. “The pathway of B cell differentiation with respect to the nature and location of potential IgE+ memory cells as well as long-lived IgE producing plasma cells in allergy is still not completely understood” [1]. We do know, however, that “IgE is continuously produced to maintain constant IgE levels in blood,” and that Th2 cells can increase that baseline.

[1] https://www.mdpi.com/2073-4409/8/9/994

[2] https://www.ncbi.nlm.nih.gov/books/NBK27117/