Note that the trial was for “stage IIB–IV melanoma that had been surgically removed prior to entering the trial.”

> lost my dad to cancer because of cancer medication

Please don’t phrase it like this. Loss is hard. But desperate people have skipped treatment because they misread something online.

I’m grateful you said this. Your comment led me down a path where I discovered it is essentially biologically impossible for his Lenalidomide to have caused stage 4 liver cancer in just a year. It turns out the liver cancer was a totally separate issue brewing silently for years, likely encouraged by a decade of TRT he was on. The severe skin issues he had a few years prior were early warning signs of his liver failing, but they got missed and masked by general dermatitis the myeloma diagnoses. Realizing the cancer meds weren't to blame actually brings me a ton of closure. I definitely don't want to scare anyone away from life-saving treatment based on my misunderstanding. Thank you.

That isn’t to say there aren’t terrible tradeoffs that have to be faced in the course of cancer treatment, and much of medicine. Pharmaceuticals seem to beget pharmaceuticals.

I lost a friend who died from complications caused by chemotherapy. That's a true statement. It's also true that she would most likely have died at least a decade earlier, maybe two decades, had she not done chemotherapy. (She was on her 3rd or 4th relapse.)

I don't mind the above wording at all, because there's another thing that happens: people seem to have this impression that if you get cancer, follow the recommended treatment, and are in remission... that you're "done", and you "won". It isn't like that. First, the treatments have serious side effects, both short and long term. Second, cancer is never gone from your life, even if it never comes back. That doesn't mean you should not do the recommended and available treatments. Your odds of survival are almost always much much higher if you do, and imo is the right thing to do for the vast majority of people. But go into it with your eyes open. You're past the point where you get to have a conventional happy ending. You'll need to figure out how to be ok with the ending that you can still have. (Which may be a happy one! But not in the way that you imagined when you were younger.)

I lost my dad to cancer because of surgical complications. All of this stuff is risky, and not treating the cancer is a valid choice that some people make. But anybody who reads an anecdote by a quasi-anonymous non-expert had better not base their care plan on that.