Yeah, Andromeda has some cool ideas (the whole Remnant thing felt like a very classic Scifi mistery) but it was stuck in classing BioWare cliches with companions loyalty quests and romances, the main character being weird chosen one, the main plot was dumb and it was barely a Mass Effect because of the disconnect from the main universe and missing some of the favorite Mass Effect things (like the Geth).

It might have been successful if it weren't a Mass Effect. Or maybe not, who knows.

I think a large part of the issue is that the sum total of ME trilogy is a hard act to follow, without aiming to sound hyperbolic it's a very bright light that outshines a lot. Anything trying to be a sequel has a difficult balancing act of being familiar versus being different and bringing new ideas in.