I think these days it's easier to run Steam in Wine than it is to run Wine in the first place. If you're running a commercial packaging of Wine for gaming, both things are trivial.

(Successfully running Windows games is its own issue: I think "Steam Deck" compatibility badging is a pretty reliable tell for Linux gaming, but on a Mac, having the game be playable is a gamble on install and again with every patch.)

If you pay for Crossover, sure. Not if you want to use the free Wine. And it used to be hard even in Crossover.