I think the benefit is supposed to be the locking feature. Any human that sees myemail+chase@domain.com and wants to circumvent your filters to get to your main inbox (typically for sales purposes) can figure out to email myemail@domain.com. With this product, the email is undeliverable unless they label their emails correctly.

Exactly. Even bots can strip the "+" and bombard you with junk. With a prefix inbox you can invent any suffix. I have a "service" prefix that I add suffixes to it when I need: "service-netflix", "service$bank", "service.newsletter-1". I don't need to pre-create each one, only "service" is enough and then any suffix locks to the sender. They can't sell your email. And they may never know to invent a new suffix because they don't know where the prefix starts. You can make it "sdfawetr" if you want.