The impossible challenge of getting HN commenters to understand that other people may be different.

That's right - its "impossible" to teach others about DOSE; how the chemical soup of the body works differently for everyone, including how environmental factors and behaviors of social interactions can affect it, and how someone may want to see an endocrinologist if they want a different outcome to their life. ;P

For a forum that very often likes to pride itself on how “enlightened” discussions are, people are so arrogantly oblivious of one of the simplest and most well-understood facts that people are different. It’s just utterly depressing to see people arguing that “introversion is a choice, you just have to try harder”.