Yes, that’s not good enough. Rodents are not humans. Then you have to deal with the dose, the setting, the difference in healthy lifespan, and a million other factors that differ from actual people in the real world.

On top of all of that, this paper did no actual research - it just mined existing literature for any chemicals with at least one paper saying that it did something cancer-related in mice or other assays.

Based on prior experience, almost certainly a substantial proportion of these papers are crap, but they don’t make any effort to figure that out (because that would be science, and therefore hard.)

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Madmallard 2 hours ago | parent | next [-]

This problem with things like this is that the real science is extremely costly to do and the usage of chemicals across the entirety of our environment is exploding borderline exponentially with time and obviously these things we didn't evolve to tolerate and low and behold so many new health issues are just skyrocketing in incidence.

So what do?

Just sit around and nitpick? Honk honk

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timr 2 hours ago | parent [-]

> Just sit around and nitpick? Honk honk

The alternative is just making things up because it makes you feel better, so I’ll take actual science.

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rdiddly 2 hours ago | parent | next [-]

That's the other extreme, not "the alternative." Science is knowing fewer things, but knowing them well (to a high degree of certainty). Making stuff up is "knowing" more things but being uncertain and/or wrong. In between the two, there's a whole spectrum. I'm willing to "know" a few more things, but know them less well. Like being pretty sure pesticide exposure is not decreasing my risk of cancer for example.

The other thing is, I would be willing to be presumptively wrong about something like this, for the sake of safety. If someone wants to add a chemical to "the environment" (a commons) then I think the burden of proving it's safe falls on them.

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timr an hour ago | parent [-]

> Making stuff up is "knowing" more things but being uncertain and/or wrong.

No, making stuff up is making stuff up. Uncertainty is what we get when we run an experiment and have some level of doubt about the outcome. What the OP proposes is to instead just do stuff to solve problems that haven’t been demonstrated, by doing things that haven’t been shown to have any effect. That’s not science - it’s religion.

Attempts to get around this by invoking the “precautionary principle”, or using broadly negative Bayesian priors, are basically just religion dressed in a lab coat. For example:

> Like being pretty sure pesticide exposure is not decreasing my risk of cancer

Completely made up. Even if you wanted to point to this paper (however bad), as evidence, it doesn't defend your specific claim.

	▲	rdiddly an hour ago \| parent \| next [-]
		That's fine.
	▲	Madmallard an hour ago \| parent \| prev [-]
		WHAAAAAAAAAT?

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Madmallard 2 hours ago | parent | prev [-]

It's not really making anything up, it's just not high on the tier list of evidence.

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abisheakp197 2 hours ago | parent | prev [-]

You are right