Remix.run Logo
bunderbunder 3 hours ago

Yes. One interesting example is that compulsive gambling is a side effect of a certain class of drugs for treating Parkinson’s disease.

https://parkinsonsjournal.com/en/parkinsons-disease/gambling...

mrguyorama 18 minutes ago | parent | next [-]

That's because parkisons drugs can upregulate a certain protein that is implicated in all forms of addiction that feature that kind of "seeking" behavior and modification of the reward system!

https://en.wikipedia.org/wiki/FOSB#Role_in_addiction

We found that if you give an addicted rat a chemical which suppresses the expression of this gene, it will improve their addiction situation, reduce seeking behaviors, etc.

We found that in 2015.

fragmede an hour ago | parent | prev [-]

Another interesting thing is that GLP-1s anecdotally treat compulsive gambling.