> same approach of casually spending a few million on agentic computation is going to solve end to end materials design or drug development."

you're not actually spending that money. it's sunk cost, as you already bought the hardware. at least for the big pharmaceutical companies for drug development. then you run your own local model, trained on special data, with special etc, etc... to the end of buying GPUs for what, 3.5-6.5M/rack or so (GB300 NVL72, Google AI summary pricing quote) becomes a bargain (vs the double digit billions you need to spend on a new drug R&D).