Bitwig natively supports Linux. I bought a license a while ago and while the cost is steep, I don't regret it at all.

The downsides are going to be the bland cross-platform UI and the general lack of plugin support on Linux. But the upside is native PipeWire support for application-specific channel audio and complex output routing options. The pack-in plugins are pretty good too, The Grid can replace a lot of your subtractive synths: https://www.bitwig.com/the-grid/

+1 for Bitwig - written by a bunch of former Ableton devs and its external plugin/module sandbox means that a badly behaving VST won't take down the entire DAW.