Ops here. Don't use musl if you care about disk size or compatibility either. For reference:

docker.io/node:26-alpine - 61MB

docker.io/node:26-trixie-slim: 84MB

gcr.io/distroless/nodejs26-debian13: 55MB

Before this post, we have issues with different, slower DNS resolution in musl.

In 2026, there in no reason other than self-inflicted compatibility and performance pain to use musl in production services.

It has it's place, for binary cross-OS distribution, and generally having an alternate C STL. But avoid for SaaS.