Though this article concentrates on the SSRIs, other meds like the SNRIs can have a similar or even worse withdrawal effect. We didn't call it "Side Effexor" for nothing.

People legitimately need these drugs, including in the short term. The problem for acute stressors once they resolve is how to get them back off.

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KurSix 5 hours ago | parent | next [-]

For something prescribed to get someone through a temporary crisis, "how and when do we get you back off this safely?" should probably be discussed at the beginning, not years later when the patient decides to stop.

	▲	sixeyes 2 hours ago \| parent [-]
		for my snri i lessened the dose by 25% and that alone cost me a week of work, i was so fucked over. when i quit this i will for sure do the thing where you open the capsules and remove a little of the contents, gradually removing more each day. i read online about people doing this and thought they were nutjobs. well, now i know.

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Paracompact 12 hours ago | parent | prev | next [-]

> Though this article concentrates on the SSRIs, other meds like the SNRIs can have a similar or even worse withdrawal effect.

And don't even get me started on tricyclics or MAOIs... no, seriously, don't get me started on them! The current generation of first-line antidepressants (SSRIs/SNRIs) might as well be free compared to the old school crazy pills.

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KurSix 5 hours ago | parent | next [-]

It's probably less "modern antidepressants are uniquely bad" and more "we got much better at starting people on safer drugs than we did at figuring out how to stop them"

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sheepscreek 11 hours ago | parent | prev | next [-]

Much of medicine (especially mental health related) is rather primitive. We are literally reverse engineering discoveries that seem to work on some other animals, and then figuring out how (to the best of our limited ability).

I liken SSRIs to carpet bombing - also their mechanism to increase seratonin in the brain is by making something else not use it (reuptake inhibition). We’re guessing that other thing isn’t a big deal. But who knows. Serotonin is produced in the gut and it controls melatonin, which controls our sleep. It’s all connected in a bizarre way.

	▲	matheusmoreira 10 hours ago \| parent [-]
		> I liken SSRIs to carpet bombing It's like inserting objects into the body's event loop and hoping it produces the desired effects as it circulates, only to find that everything reacts to the event, not just the parts we want. https://news.ycombinator.com/item?id=37029912

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SV_BubbleTime 11 hours ago | parent | prev [-]

> school crazy

Yep, that’s how I associate SSRIs.

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ImHereToVote 27 minutes ago | parent | prev | next [-]

"People legitimately need these drugs"

First. Do no harm.

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12 hours ago | parent | prev [-]

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