0 issues using nickelmenu out of the box.

I recommend enabling ssh (native kobo feature) so it's easier to modify the config without needing to plug in, though obviously this is optional.

If you connect over SSH, I would recommend not touching system files. The new kobos don't have a removable SD card so if you corrupt the system files and it can't boot, you need to either do some PCB surgery or get a new mainboard.