Can someone smart tell me how to profit from this if I believe this (plus everything else) is going to spiral into huge crisis?

If you have to ask, you’re too poor or powerless to properly profit.

The best way to derisk would be to get out of the US and surrender your citizenship. But the alternatives may not be all that much better (France has marginally lower debt to gdp, japan has much higher, to give two examples).

Go ask a (capable, preferably open) LLM. If it doesn’t give you a direct answer it will give you enough of a starting point to start asking more questions.

(This is not financial advice)

Learn the ways of the kangaroo.

GenX/Millennial retirement communities abroad. There won’t be any SS funds left for that generation so they won’t be able to retire in the US.

In all seriousness - this level of debt will probably require somewhat high rates of inflation to reduce. I'd expect the inflation baseline to be relatively high over the next few decades.

High inflation helps those who borrow with fixed terms. If you have a mortgage, don't pay it off. Don't pay off low interest rate debt. Consider acquiring a responsible amount of low-medium interest rate debt. Put your money into stocks and other assets that will appreciate with inflation.