If they're zoned like heavy industry, that seems fine for any noise/ heat etc. If they're zoned for light industry or similar to office buildings like the other comment says I feel like that could have different impacts - an office building will have some of this but probably has much less equipment and energy needs, less venting heat out maybe?

But if we're going to keep factories and chemical plants away from housing we can keep data centers over with them I think. Out of sight, out of mind, less chance of local protestors, maybe even closer to good power plants for transmission. Everyone wins?

a couple things to note that complicate it:

* a bunch of places didn't have the foresight to actually put buffers between industrial and residential zoned areas (either due to space limitations and/or poor planning)... sometimes people only notice when the empty lot they lived next to for a decade actually gets something built

* currently some protests are whipping up enough fervor where location doesn't really factor, people are fighting against any data centers within city limits at all