Sildenafil [0] was synthesized to treat high blood pressure. Erectile disfunction was a side effect that raised much more interest.

Tadalafil [1] followed the path of Sildenafil about the phosphodiesterase type 5 (PDE5) enzyme inhibitor.

Help to live longer was the main objective since the beginning.

I invested heavily in ICOS when they launched, they had Bill Gates money and were looking for ways to extend lifespans and solve inflammation.

And all we got was another boner pill.

giantg2 an hour ago | parent | next [-]

Quanity and/or quality of sex shows correlation with longer lifespan. Maybe this is a roundabout way to get there...

	▲	joezydeco 35 minutes ago \| parent \| next [-]
		I do admire the fact that someone with a sense of humor at ICOS named the molecule TADA-lafil.
	▲	croemer an hour ago \| parent \| prev [-]
		Healthy people have more sex I guess?

fny 2 hours ago | parent | prev | next [-]

Lifespans and inflammation are ironically harder problems.

Yes, but we don't want medical science to go soft by focusing on the easy problems.

	▲	miguelxpn 24 minutes ago \| parent [-]
		But the whole point of those pills is that it didn't go soft anymore!

fragmede 2 hours ago | parent | prev [-]

During your extended lifetime, wouldn't you like to be able to have a boner, though?

	▲	NordStreamYacht 2 hours ago \| parent [-]
		Picasso managed it all without these meds.