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teleforce 2 hours ago

For non-invasive heart disease risk prediction nothing beat ECG, period.

Somehow American Heart Association and its European counterpart are in denial, and still pushing dinasour screening mechanism with very low accuracy for heart disease risk prediction.

The standard risk model for CVD based on PREVENT (US) and SCORE-2 (Europe) like parameters are very poor as reported in the recently published paper on the their accuracy performance by the Swedish team [1]. As all CVD risk stratification with cardiologist review (expert-in-the-loop), the most important accuracy metric is sensivity/recall (avoiding false negative that will escape review) of PREVENT and SCORE-2, 26% and 48%, respectively.

The paper alternative proposal increased the sensitivity to 58% by performing clustering instead of conventional regression models as practiced in the PREVENT and SCORE-2.

These type of models including the latest proposal performed very poorly as indicated by their otherwise excellent and intuitive display of graphical abstract results [1].

[1] Risk stratification for cardiovascular disease: a comparative analysis of cluster analysis and traditional prediction models:

https://academic.oup.com/eurjpc/advance-article/doi/10.1093/...

er4 34 minutes ago | parent | next [-]

Get as many scans you can under insurance. Data is king and Claude happens to chew it all pretty well. Apple Health data by itself and family history is enough to make a starter PDF for your cardiologist.

Getting an ECG, EKG, TTE, CAC, carotid duplex US, lipid panel, CMP, TSH, 25-OH Vit D, B12 + folate were what my cardio recommended before appointment #2 on hypertension. Both of us are data guys.

sscaryterry an hour ago | parent | prev | next [-]

How many ECGs can you sell vs how many other snake-oil products? :)

(Edit: This is intended to be sarcastic. I agree 100% with the comment)

(Edit 2: Added the smiley face)

Aerroon an hour ago | parent | next [-]

>How many ECGs can you sell vs how many other snake-oil products?

A lot, probably. You could sell people on the idea that it should be a part of your yearly health screening.

"And if you really care about your health you should do them every 3 months to catch problems early!"

or some such.

sscaryterry an hour ago | parent | next [-]

This will work short-term sure, but after about lets say, 3 years of no adverse findings, the average person will not take it seriously anymore.

alooPotato 17 minutes ago | parent [-]

Huh? I get a blood panel every year and 90% of the things it looks for are normal year after year. But there is always 1 or 2 things flagged that I need to pay attention to.

An ECG if it was just part of the normal yearly panel of things that get looked at I don't think ppl will stop doing it just because it doesn't find something right away

sscaryterry 7 minutes ago | parent [-]

> the average person

I do not consider the average HN commenter to be average.

clickety_clack 20 minutes ago | parent | prev [-]

“You’re waiting 3 months between ECGs?”

sscaryterry 6 minutes ago | parent [-]

Whistle: Hope you didn't burn those arteries there mate :)

fluoridation an hour ago | parent | prev | next [-]

You can still sell snake oil that's purported to improve ECGs.

sscaryterry 44 minutes ago | parent [-]

We should talk, if you can't beat 'em, join 'em :)

justsomehnguy an hour ago | parent | prev [-]

Poe's law in a full swing.

sscaryterry an hour ago | parent [-]

I didn't know... Thank you

fatcatsbestcats an hour ago | parent | prev [-]

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