> So has anyone managed to separate the effects of semaglutide from the effects of weight loss?

In general? Yes. For this specific thing? We haven't even really shown the effects matter for humans.

> If this is caused by the weight loss, it is a little disappointing that public health didn't act quicker - lots of people have been overweight for a century now, so literally 10's of millions of people could have been saved from dementia had action been taken 100 years ago.

Public health has been banging the drum on obesity for decades now. But humans on the whole aren't built to be able to resist hyper palatable calorie dense cheap foods.

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OptionOfT 4 hours ago | parent [-]

We're too soft on companies, but equally too hard on people who have a food addiction.

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SubmarineClub 4 hours ago | parent [-]

Nah, we’re still too soft on people. It’s really not hard to eat a healthy diet.

	▲	jaggederest 3 hours ago \| parent \| next [-]
		As someone who has experienced so many different sides of this, you have zero clue the degree to which your appetite and ability to suppress it is hormonal until you get hormonally compromised (and then fix it, in my case, happily) Blaming individuals for a public health crisis affecting 40% of the population is absolutely silly. There are a lot of individuals like me, who overeat behaviorally, but that doesn't explain the scale of the issue. maybe 8-10% of the population has some sort of eating disorder, the other 30% are just regular people eating an american diet.
	▲	NorthSouthNorth 4 hours ago \| parent \| prev \| next [-]
		I think this is easy to say as a healthy eater (I am one too, always have been). However, unlearning a lifetime of bad habits is hard. But yeah, it's costing nations billions that could be better spent.
	▲	agos an hour ago \| parent \| prev \| next [-]
		If it’s not too hard why are people not doing it?
	▲	ThrowawayTestr 4 hours ago \| parent \| prev [-]
		It's really not hard to not drink. It's really not hard to not do heroin. It's really not hard to...