I’m also active and fat. And to me being active is more important than losing weight; I’d rather continue to do those long 2000kcal bike rides on weekends than having a healthier BMI. I’ve heard stories of my own friends bonking during a ride and I decided that I wanted to err on the side of overeating. So semaglutide doesn’t interest me. You aren’t the only one I’ve heard who started to have no energy after being on semaglutide.

That said the dementia benefit mentioned in the article still intrigues me.

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eapressoandcats 5 hours ago | parent | next [-]

I know people for whom GLP-1s made them lose weight, have a better relationship with food, and reduce their intrusive thoughts, and left them far more able to be active.

I feel like we’ll eventually find out that how well GLPs work is going to depend on the “why” someone has extra weight.

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NorthSouthNorth 3 hours ago | parent | prev | next [-]

People bonk because they're not eating enough DURING the ride. I'll eat (actually mostly drink) like 120-200g carbs on longer rides. Record is 700g during a 200km ride. I've seen big guys bonk too. It has very little to do with your BF% (although this is nuanced based on power zones and training 'durability' etc, etc).

	▲	01100011 2 hours ago \| parent [-]
		Going back to my endurance days, I think people bonk because they aren't adapted. After a year or so of pushing through the bonk, and growing up with hypoglycemia if I didn't eat frequently, I got to where I could start out at 5am on an empty stomach and not eat until noon or later. If I did bonk, I'd sip V-8(yeah, really) and instantly recover.

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loeg 5 hours ago | parent | prev | next [-]

I'm on tirzepatide, a competitive athlete, and have no idea what GP is talking about.

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01100011 5 hours ago | parent | next [-]

Being a competitive athlete is probably why you have no idea what I'm talking about (and maybe you're not in your 50s). You have a reason to keep your momentum and you are likely more regularly active than I was. Sure I lifted weights, but it was only 2-3 days a week for maybe 6 hours total.

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loeg 5 hours ago | parent [-]

Maybe start lifting weights again? 50 isn't a death sentence; I know a lot of competitive 50s-year-olds.

	▲	01100011 2 hours ago \| parent [-]
		I'm trying but I've got a toddler and now it seems like every joint hurts. No time to get to a gym and no room for a decent home gym. I did start to do back day again at the Y when we go on the weekend for the pool. We'll see...

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mathgeek 5 hours ago | parent | prev [-]

People who eat well below their maintenance calories tend to have lower energy levels. That's the most likely explanation.

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anon291 4 hours ago | parent | prev | next [-]

Being active is great but fat is still dangerous. Let's not lie to ourselves.

> decided that I wanted to err on the side of overeating

The reason you bonk is because you've run out of sugar in your muscles not fat

	▲	kccqzy an hour ago \| parent [-]
		True, but sugar can be converted to fat in the body. If you eat too much sugar before/during a ride, the extra sugar becomes fat.

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paulpauper 4 hours ago | parent | prev [-]

There are so many active overweight or obese guys, whether it's cycling, swimming or hiking .This myth that inactivity = obesity or that activity fixes obesity or being overweight, need to die. It's not that simple. Hunger signals and how the body partitions/uses food is only orthogonal to activity.