Didn't even bother looking into it because there's obviously not enough data yet to say anything substantial about GLP-1s and Alzheimers. But your comment should probably be the top.

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danielmarkbruce 6 hours ago | parent | next [-]

GLP-1s have been used for over 20 years. There likely is enough data to say something, even if it's not water tight.

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akiselev 4 hours ago | parent [-]

They've been used for over 20 years but until they became a weight loss drug recently, almost all of the research was on diabetics which introduces two confounding factors: diabetes and the diets diabetics already have to follow to manage the disease. It's hard to draw any conclusions when the results are muddied by those two factors.

	▲	danielmarkbruce an hour ago \| parent [-]
		[dead]

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rogerrogerr 6 hours ago | parent | prev | next [-]

I’m not an expert on this, but haven’t GLP-1’s been used for quite a while on more limited scopes? So maybe there’s a cohort of people that could approach statistical significance.

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toast0 6 hours ago | parent [-]

IIRC, mostly used to help with type 2 diabetes... But effects on that cohort may not generalize to the general population.

	▲	Muskwalker 5 hours ago \| parent [-]
		This particular study was done on people without diabetes, at least.

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SubiculumCode 4 hours ago | parent | prev [-]

Cognitive Decline != Alzheimer's. There are other forms of cognitive decline in aging.