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throwaway2037 13 hours ago

Here is the original study: https://link.springer.com/article/10.1007/s00394-026-04038-z

Weirdly, I cannot copy text from that page. What am I doing wrong?

Regardless, here is the result summary:

    > Higher coffee intake groups showed lower total and visceral fat and higher skeletal muscle mass, while BMI was comparable across groups. Inverse correlations were observed between coffee intake and circulating branched-chain amino acids (BCAAs) in both sexes. In men, higher coffee intake correlated with a more favourable glucose-insulin profile. Multivariable-adjusted models revealed a distinct hormonal pattern: positive associations with total testosterone (β = +0.29 nmol/L per cup/day), bioavailable testosterone, and sex hormone-binding globulin (SHBG), alongside inverse associations with free testosterone and the free androgen index (FAI). In women, hormonal associations were more limited, with positive associations for SHBG and inverse associations for free testosterone and FAI.
This part: "positive associations with total testosterone (β = +0.29 nmol/L per cup/day)". For testosterone, 1 nmol/L ≈ 28.8 ng/dL. So: +0.29 nmol/L ≈ +8.4 ng/dL per additional cup/day.

Really, this will have no meaningful impact on your health. It is widely discussed by TRT (testosterone replacement therapy) doctors that supplements that can increase your total test by 100ng/dL will have no meaningful impact. Literally, you need to drink 12 cups of coffee per day to get a ~100ng/dL improvement. You are going to have a lot of second order effects from drinking 12 cups of coffee per day! I would never recommend it.

doubled112 13 hours ago | parent [-]

I often drink a 12 cup pot in a day. No noticeable effects.

Why are coffee cups smaller than cups?

Maybe I’m just slow, but it makes doing the mental math a lot more difficult than it needs to be. Maybe I just need more coffee.

throwaway2037 7 hours ago | parent [-]

I cannot tell: Is this sarcasm? Really: That is not healthy to consume so much caffeine per day, unless you are drinking decaf. Depending upon your size of coffee, they are mostly 6-8 fluid ounces, or about 70-90mg of caffeine per "cup".

Here is a quote that I found:

    > For most healthy adults, up to 400 milligrams of caffeine a day—about four 8-ounce cups of brewed coffee or 10 cans of cola—is considered safe and not linked to negative health effects, according to the U.S. Food and Drug Administration (FDA).
There is absolutely no way that it is safe to "often" drink 12 cups of coffee per day.