Water and food have a milder risk profile. The FDA (https://glp-1.health/blog/glp1-obesity-eligibility-bmi-chart...) recommends "GLP-1 weight loss medications (Wegovy, Zepbound) if your BMI is 30 or higher, or if your BMI is 27 or higher with at least one weight-related health condition such as high blood pressure, type 2 diabetes, or sleep apnea". This is because there are side effects such that GLP-1 meds have not been shown to produce a net positive benefit-to-risk ratio for people who are only mildly overweight.

> This is because there are side effects such that GLP-1 meds have not been shown to produce a net positive benefit-to-risk ratio for people who are only mildly overweight.

Importantly, this is different from "GLP-1 meds have been shown not to produce a net positive benefit-to-risk ratio"

Anyway nearly all of the side effects for these drugs are just discomfort. Not even really obvious they should be called "risks." Meanwhile, the vast majority of Americans who are not already diabetic or have HTN will soon, and it would be quite a surprise to learn these drugs don't have protective effect.