Yup, totally doable. Of course, it’s a point to point link so if you want to build a whole cluster that way then you’ll need a lot of usb-c ports or you’ll need to make more of a mesh topology.

I believe MacOS supports it via the usual network control panel. I’ve used it for transferring data from an older laptop to a newer one. The cable is more expensive than fiber, last time I checked.

I have also used a USB 4 cable to network two MacBook Pros to one another and can confirm that it was very simple to connect and it was fast as heck. The USB 4 cable I used was rated for up to 40 Gbps.