> what should be done about open weight bioweapon and cyber-offense capabilities? Is it simply the cost of freedom that we should allow attackers to access these tools?

In short, yes, it's the price of freedom. As others have said, blocking these models won't stop the "bad guys", but will hinder defenders researching/responding to bioweapons and cyber-offenses.

But you're right that there's a lot of difficult nuance aand we should think carefully about its implications. So here's another nuance to think through.

If AI is as powerful as some believe, then there's much greater danger to give a small subset of society the privilege to gate keep who has access to these tools.

"Power corrupts and absolute power corrupts absolutely." Lord Acton