Yes life was better and food and drugs were safer before the FDA.

In 1600 travel was slow, and safety pins hadn't been invented.

But that doesn't mean safety pins sped up travel.

Non-poisonous food is what economists call a 'normal good'. See https://en.wikipedia.org/wiki/Normal_good

> In economics, a normal good is a type of a good for which consumers increase their demand due to an increase in income, unlike inferior goods, for which the opposite is observed. When there is an increase in a person's income, for example due to a wage rise, a good for which the demand rises due to the wage increase, is referred as a normal good. Conversely, the demand for normal goods declines when the income decreases, for example due to a wage decrease or layoffs.

> Whether a good is categorized as a normal good or an inferior good is based on empirical observations, not some essential element of a good. Indeed, the same good may be a normal good for one group of consumers and an inferior good for another group. For example, for moderate-income consumers, a BMW 3 Series car might be a normal good, but for an upper-income group, it might be an inferior good.[1]

That means the null hypothesis is that food and drugs will be safer in rich countries. (Conversely, food and drugs will be less safe in poorer countries. And to a first approximation, that's independent of regulation: India has all kinds of rules for all kinds of things, but I'd still trust a random product I buy in Switzerland more than one I buy in India. Even though the Swiss will probably might have fewer and looser rules on the books.)

Of course, second order effects exist; and regulations often codify what people demand anyway.

Btw, from what I've read the big controversy with the FDA is around requiring efficacy for drugs. People are fairly ok with the safety requirements.