Also, highly related, in the previous paragraph, they say: "We know a lot more about the biology of disease - although God knows, not nearly enough".

Anyone smarter than a 10 year old would not we actually know almost everything about car design. How it works is not at all hidden. We have iterated on pretty much the same thing for 100 years. The current state is about efficiency, materials and manufacturing.

When you have deep knowledge and experience in a field you will get near 100%.