I'd say probable in some situations - maybe more effect for people who are not eating well. I am not someone who takes or used drugs or alcohol - but the 90s I used pure low dose of creatine at about half teaspoon a day to help repair neck muscles damaged from treated-too-late whiplash. At the time my diet was probably poor even though I ate meat daily, had a low grade cold I hadn't been able to shake off for three years, and would blow a fuse easily around idiotic BS. After a few weeks I was pretty mellow and easy going, not to mention the cold had finally cleared up. I stopped taking it for various reasons, needing to be on top of BS quicker was one of those reasons. Later in life I have used it but not with the same pronounced effects.