Icariin too is a PDE5A inhibitor and a cGMP elevator.[1]

The antifungal drugs itraconazole and posaconazole directly have the downstream effect NPC1 inhibition followed by a reduction in lysosomal cholesterol accumulation.[2][3]

[1] https://pubmed.ncbi.nlm.nih.gov/17169663/

[2] https://pubmed.ncbi.nlm.nih.gov/31919352/

[3] https://pubmed.ncbi.nlm.nih.gov/40516874/