Space data centers are an intrinsically cool idea, and honestly I hope we see at least one for the sheer marvel of such a project. But to be cost efficient, it has to be cheaper than rural US, cheaper than buying some island, cheaper than setting it up on a converted freighter ship and tanking the fuel in, etc.

BUT once Earth has a fully paid off space elevator the unit economics will make sense, or if we have orbital space factories and don't have any lift costs, etc. It's all possible, but at a 50 year+ timescale and immense investment. All of which I hope for because I'd like to see more space development and exploration.