You can run larger models by offloading to SSD (for weights), it's just slow so people don't do it all that much. But you can get back at least some of that performance by using either MTP (at least for dense models; not effective for sparse MoE models unless you're batching them already and have VASTLY more parallel compute than you'd know what to do with) or batching multiple requests in parallel (note, this hurts throughput for your single sessions but running more sessions in parallel still boosts your total amount of inference. This requires careful management of memory requirements for your context/KV cache, and Qwen models tend to be KV-cache heavy).

Broadly speaking, this ultimately pushes local inference towards a challenging world where you use SSD offload for weights as a matter of course; then smaller requests (or requests sharing the bulk of their context, e.g. subagent swarms) can be batched together and run quickly in aggregate, but running very large contexts will actually limit you to single-session inference and require swapping out even the KV cache itself to some external scratch SSD, further hurting your performance. Then feel free to add wide use of MTP in a probably futile effort to go back to tolerable tok/s numbers.