Life needs energy to be moving around, without energy exchanges, by very definition, nothing interesting happens.

An inert element, for that reason is just not suitable for life. It's not a reasoning based on anthropocentricity it's just basic chemistry and mathematics. If things can't assemble together, and combine, and form more complex structures, you can't get life. If you could get life out of simple basic atoms, we would see life everywhere, and we would be creating it everyday in labs. We don't.

Doesnt mean life can't exist there by using other elements, but detecting helium is not increasing the likelihood of finding life there at the very least.