Anyone got a quick primer on what 7-Oh is? That's a new term for me and the web search doesn't seem reliable.

I first learned of kratom in the last year from Elijah Lemard

https://www.youtube.com/watch?v=0z5ixJIqbGY&t=267s

He's an odd guy who likes to investigate some really dodgy stuff. And I suspect many here on HN would appreciate him.

That led to 7-OH showing up in my feed at some point. In a nutshell, it's the strongest of the active compounds in the kratom plant, that binds to opioid receptors. 7-OH is the marketing name for the alkaloid 7-hydroxymitragynine that is being refined from kratom. It's not clear to me if it's simply extracted, or as some quick research suggests, it might also be a chemical alteration of the more commonly occurring compound in kratom mitragynine.

Anyway, this stuff looks super habit forming, and, of course, the refined version is that much more addictive.

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simulator5g a day ago | parent | prev | next [-]

Synthetic opioids sold at gas stations.

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switchbak a day ago | parent [-]

Here in Canada you're not allowed to 3d print a modded grip for the rifle you're not allowed to buy, but in the USA you can get OPIOIDS at a GAS STATION! ... things are definitely different down there.

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mghackerlady a day ago | parent | next [-]

To be fair, it is a relatively weak one that people claim has medicinal benefits

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mothballed a day ago | parent | prev [-]

But the prison sentence once caught is much shorter in Canada.

	▲	switchbak 20 hours ago \| parent [-]
		The prison sentence for being caught doing legal things is surprisingly short.

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ChrisArchitect a day ago | parent | prev | next [-]

https://en.wikipedia.org/wiki/7-Hydroxymitragynine

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IAmGraydon a day ago | parent | prev | next [-]

Kratom is a leaf that is primarily farmed in Asia which contains the active ingredient Mitragynine, which has some very mild partial-agonist opioid effects. When kratom is consumed, your liver converts a very small amount to a MUCH more potent molecule called 7-hydroxymitragynine. As with all natural drugs, some asshats in a lab decided to figure out how to create the latter molecule semi-synthetically and in bulk. They pressed them into pills and sell them in head shops and some gas stations. It's pretty addictive, nasty stuff.

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dijksterhuis a day ago | parent | prev [-]

recent jon oliver last week tonight segment on kratom and the wider 7-oh stuff.

Gas Station Drugs: Last Week Tonight with John Oliver (HBO) https://www.youtube.com/watch?v=mRZqHzDG_c8

> John Oliver discusses the sprawling industry of “gas station drugs” – a world of questionable supplements and boner pills – which is posing a risk to the public by putting underregulated substances over the counter, and, more importantly, could prevent people from saving up for a Honda Civic.