Remix.run Logo
robobro 3 hours ago

Dextromethorphan is definitely not a placebo. Take enough and you'll go to space and meet God. Smaller doses produce euphoria and dissociation, which, even if they don't make the cough go away, makes it easier to tolerate a cold -- same reason antitussives have historically contained alcohol, cannabis extract (which may incidentally work as bronchodilator but was not the reason I imagine it was in antitussives)

Funny amphetamine used to be an over the counter cold medicine, which the article doesn't mention despite talking about the meth precursor?

Fine article but these two details stuck out to me while reading it.

23 minutes ago | parent | next [-]
[deleted]
Sohcahtoa82 2 hours ago | parent | prev | next [-]

> Dextromethorphan is definitely not a placebo.

It definitely works for me. It'd be wild if for all 44 years of my life, it's only worked because of the placebo effect.

The article mentions phenylephrine, and that shit definitely doesn't work. Not even a placebo.

EPWN3D 36 minutes ago | parent | prev | next [-]

Yup. The only upside to being sick is that I get to take NyQuil before going to sleep and have trippy as fuck dreams.

nerdsniper 2 hours ago | parent | prev | next [-]

The left enantiomer of methamphetamine (exact same chemical formula and structure, just mirror symmetry) is also an OTC decongestant.

butlike 2 hours ago | parent [-]

Vicks

nerdsniper 2 hours ago | parent [-]

Only historically. No Vick's brand product has contained it since 2016. The only "brand" name I'm aware of currently is Benzedrex.

gavinray 2 hours ago | parent [-]

Benzedrex is not l-Methamphetamine, it is Propylhexedrine

nerdsniper 37 minutes ago | parent [-]

Ah indeed, I misremembered. That is also a very similar compound, identical structure but more saturated carbon bonds (non-aromatic ring). It's always delightfully silly to get your own correction corrected!

https://www.vumc.org/poison-control/toxicology-question-week...

Melatonic 40 minutes ago | parent | prev | next [-]

Very relevant username

jona-f 3 hours ago | parent | prev [-]

Came here to say this, the author is hating on dextromethorphan like he never robotripped before. But then, overdosing dxm isn't all that healthy and I'd recommend ketamine if you want to experiment like that.

MisterTea 2 hours ago | parent [-]

> But then, overdosing dxm isn't all that healthy and I'd recommend ketamine if you want to experiment like that.

Ketamine is neurotoxic itself and can cause permanent brain damage. I can't find the info but there was someone in the tech industry who accidentally overdosed and suffered a two year bout of severe debilitating depression culminating in suicide.

sph 2 hours ago | parent | next [-]

Sorry to say, we shouldn't really base our opinion on drug safety from people who accidentally overdose or are generally reckless with drugs. There's people who drink for the first time and end up in the hospital.

If you want to do it the smart way, just consult erowid.org and use a little common sense.

https://erowid.org/chemicals/ketamine/ketamine_faq.shtml

john_strinlai 2 hours ago | parent | prev | next [-]

>I can't find the info but there was someone in the tech industry who accidentally overdosed and suffered a two year bout of severe debilitating depression culminating in suicide.

i believe you are referring to Felix Hill.

https://docs.google.com/document/d/1-jBoSEVlryiX1IaSzV4vKuih...

"On mental health, psychedelics and life

This is a story about mental health, psychedelics, psychology and the mind. It is a story about the joy of family, the joy of friends, the joy of being in love, and the joy of doing scientific research. It is a story about life, the world, and how amazing they both are.

After 18 months of intolerable torture, and after many months of consideration I have decided to end my life."

fooglove34 2 hours ago | parent | prev [-]

one off experience of someone in a stressful job. are we gate keeping?

jmalicki 2 hours ago | parent [-]

It is entirely reasonable to say that it should be RX-only to be monitored by a physician for these reasons.