I can't go into specifics, but I use LMDB for the commandline application I maintain for my employer. I also extended it into a web service for internal use. As long as you stick to the safe LMDB options, which are the default options, it's reliable. The documentation clearly outlines what safety guarantees you lose when you enable/disable certain options: http://www.lmdb.tech/doc/group__mdb.html#ga32a193c6bf4d7d5c5...

I had a situation where the web service's writes were slowing down to an unbearable crawl because the number of entries in the database were reaching tens of billions of entries. Thankfully, the users never experienced the slowness. The website stayed nice and fast, even though the background updates were extraordinarily slow. The issue was fixed by sharding the databases.