I have three Synology boxes:

1. backup, an RS422+ (w/ 2GB): 4x8TB RAID6

2. storage, RS818+ (16GB): 4x12TB RAID0 (everything not easily replaced is backed up)

3. san, an RS2418+ (64GB): 8x1TB SSD RAID10, and 4x5TB RAID10

I can't picture too much of a reason to drive it through the API, or at least not yet - still getting it all finalized. But I also managed to figure out IPv6 with Xfinity across my VLANs and SLAAC.

I have 2 Synology boxes, both DS1618+. The first one is my media storage, the other one is a backup target for both the media storage and other devices on the network. I also don't use the API, these are just "dumb" storage boxes that exist to store. No real configuration here from my perspective.